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| Product Name | QPRT, 1-297aa, Human, His tag, E Coli |
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| Description | MW: 32.9 kDa (317aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Hun |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Nicotinate nucleotide pyrophosphorylase (carboxylating); Nicotinate nucleotide pyrophosphorylase carboxylating; Quinolinate phosphoribosyltransferase; QPRTase; QAPRTase] |
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| Gene, Accession, CAS # | QPRT, Gene ID: 23475, Accession: NP_055113 |
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| Catalog # | MBS203645 |
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| Order / More Info | QPRT, 1-297aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Delaney J., et al. (2005) Arch Toxicol. 79 (2):208-223.; Eads J C., et al. (1997) Structure. 5:47-58.; |
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