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Product Name | FGF9, Recombinant, Human |
Description | Purity ~95% (SDS-PAGE). FGF-9 is both an autocrine and paracrine prostatic growth factor expressed by prostatic stromal cells. FGF-9 induces osteoblast proliferation and new bone formation in a bone organ assay. FGF-9 is produced by many prostate cancer cells and contributes to prostate cancer-induced new bone formation. Also, it may participate in the osteoblastic progression of prostate cancer in bone. It is also an autocrine and/or paracrine neurotrophic factor that promotes the survival of motoneurons and upregulates choline acetyl-transferase activity. FGF-9 enhances survival of AChE-positive neurons and increases their mean soma size. It also up-regulates their choline acetyltransferase activity as potently as NGF and the effect is greater than that elicited by bFGF, CNTF, or GDNF. FGF-9 acts as a survival factor for neurons but does not promote neurite outgrowth. FGF-9 has been shown to mediate its effects by binding to FGF receptors. It efficiently activates the FGFR2c splice form of FGFR2 and the FGF |
Size | 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | FGF9, Recombinant, Human (FGF-9, Glia-Activating Factor, GAF, Heparin-Binding Growth Factor 9, HBGF-9, Fibroblast Growth Factor 9) |
Gene, Accession, CAS # | SwissProt: P31371 |
Catalog # | 500008 |
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Order / More Info | FGF9, Recombinant, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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