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Product Name | FGF10, Recombinant, Human (FGF-10, FGFA, Keratinocyte growth factor-2, Fibroblast Growth Factor 10) |
Description | Purity ~95% (SDS-PAGE). FGF-10 is involved in the initial budding as well as the continuous outgrowth of vertebrate limbs. FGF-10 mRNA is expressed preferentially in neurons but not in glial cells and may have a distinct role in the brain. Human FGF-10 is mitogenic for fetal rat keratinizing epidermal cells but not for NIH 3T3 cells. Recombinant FGF-10 induces the proliferation of human urothelial cells in vitro and induces the proliferation of transitional epithelium. FGF-10 is secreted by cultured mouse pre- adipocytes, prevention of FGF-10 signaling inhibits subsequent differentiation. The ability of embryonic fibroblasts derived from FGF-10 knock-out mice to differentiate into adipocytes is also impaired. Source: Recombinant protein corresponding to human FGF10 expressed in E. coli. Molecular Weight: ~19kD Biological Activity: ED50 was determined in a NIH/3T3 cell proliferation assay in the range of 0.05-0.5ng/mL. Endotoxin: <1EU/ug (LAL) |
Size | 25ug, 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | SwissProt: O15520 |
Catalog # | 499988 |
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Order / More Info | FGF10, Recombinant, Human (FGF-10, FGFA, Keratinocyte growth factor-2, Fibroblast Growth Factor 10) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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