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| Product Name | FGF9, Recombinant, Human (FGF-9, Glia-activating factor, GAF, Heparin-binding growth factor 9, HBGF-9) |
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| Description | Purity ~95% (SDS-PAGE). FGF-9 is an autocrine and paracrine prostatic growth factor expressed by prostatic stromal cells. FGF-9 induces osteoblast proliferation and new bone formation in a bone organ assay. FGF-9 is produced by many prostate cancer cells and contributes to prostate cancer-induced new bone formation. It also may participate in the osteoblastic progression of prostate cancer in bone. It is also an autocrine and/or paracrine neurotrophic factor that promotes the survival of motoneurons and upregulates choline acetyl-transferase activity. FGF-9 enhances survival of AChE-positive neurons and increases their mean soma size. It also up-regulates their choline acetyltransferase activity as potently as NGF and the effect is greater than that elicited by bFGF, CNTF, or GDNF. FGF-9 acts as a survival factor for neurons but does not promote neurite outgrowth. FGF-9 has been shown to mediate its effects by binding to FGF receptors. It efficiently activates the FGFR2c splice form of FGFR2 and the FGFR3b an |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P31371 |
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| Catalog # | 500007 |
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| Order / More Info | FGF9, Recombinant, Human (FGF-9, Glia-activating factor, GAF, Heparin-binding growth factor 9, HBGF-9) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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