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| Product Name | FGF-23, Recombinant, Human (Fibroblast Growth Factor-23) |
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| Description | Purity ~95% (SDS-PAGE). The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Source: Recombinant protein corresponding to 228aa residues from human FGF-23, expressed in E. coli. Molecular Weight: ~22.5kD Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQH |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Fibroblast Growth Factor-23 |
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| Gene, Accession, CAS # | FGF23, SwissProt: Q9GZV9 |
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| Catalog # | 219756 |
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| Order / More Info | FGF-23, Recombinant, Human (Fibroblast Growth Factor-23) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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