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| Product Name | PAPPA, Recombinant, Human, Western Blot Control |
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| Description | Purified (SDS-PAGE). PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems. Recent studies have shown that levels are elevated in patients with unstable angina or acute myocardial infarction. PAPP-A is also produced in high concentrations during pregnancy and is released into the maternal circulation. Low levels of PAPP-A have been linked with a number of foetal chromosomal abnormalities, as well as pre-eclampsia and stillbirth. Source: Recombinant corresponding to aa81-271 from `Jelly-Roll' domain fragment of human PAPP-A, fused to 6x His-tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot as a control. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | PAPPA, Recombinant, Human, Western Blot Control (Pappalysin-1, Insulin-like Growth Factor-dependent IGF-binding Protein 4 Protease, IGF-dependent IGFBP-4 Protease, IGFBP-4ase, Pregnancy-associated Plasma Protein A, PAPP-A) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P6000-83A |
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| Order / More Info | PAPPA, Recombinant, Human, Western Blot Control from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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