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| Product Name | RIPK2, Active |
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| Description | RIPK2 (RIP2; RICK) is a death domain-containing protein kinase. Inohara identified cDNAs encoding a predicted 540-amino acid protein RICK, which contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain. Inohara also demonstrated that RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway (1). McCarthy found that overexpression of RIP2 signaled both cell death and NF-kappa-B activation (2). Thome reported that RICK specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 (3). Chin generated Ripk2-deficient mice and concluded that RIP |
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| Size | 5 µg |
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| Concentration | 5µg/50 µl |
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| Applications | RUO |
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| Other Names | RIPK, receptor-interacting serine-threonine kinase 2, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, Short name=CARD-containing IL-1 beta ICE-kinase, RIP-like-interacting CLARP kinase, Receptor-interacting protein 2, Tyrosine-protein kinase RIPK2 |
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| Gene, Accession, CAS # | RIPK2, Gene ID: 8767, Accession: O43353 |
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| Catalog # | 7747-5 |
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| Price | |
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| Order / More Info | RIPK2, Active from BIOVISION, INC. |
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| Product Specific References | n/a |
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