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Product Name | Myostatin Fusion Protein, Recombinant, Human, Propeptide |
Description | Purity ≥ 95% (SDS-PAGE); Two-step procedure using size exclusion chromatography before and after refolding. Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo. Description: 28kD protein containing 243 amino acid residues of the human Myostatin Propeptide and 5 additional amino acid residues. MG NENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVK |
Size | 5ug, 25ug |
Concentration | n/a |
Applications | ELISA WB |
Other Names | Myostatin Fusion Protein, Recombinant, Human, Propeptide (Growth Differentiation Factor 8, MSTN, gdf8) |
Gene, Accession, CAS # | n/a |
Catalog # | M9875-01C |
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Order / More Info | Myostatin Fusion Protein, Recombinant, Human, Propeptide from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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