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| Product Name | BMP-2, Recombinant, Human, Animal Free (BMP-2A) |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis, and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26kD protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BMP-2A |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208605 |
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| Order / More Info | BMP-2, Recombinant, Human, Animal Free (BMP-2A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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