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| Product Name | BMP-4, Recombinant, Human (BMP-2B, DVR4) |
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| Description | Purity ≥97% by SDS-PAGE gel and HPLC analyses. Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36kD homodimeric glycoprotein. Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. AA Sequence: HHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). Endotoxin: <0 |
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| Size | 1ug, 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143294 |
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| Order / More Info | BMP-4, Recombinant, Human (BMP-2B, DVR4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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