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| Product Name | Recombinant Human Transforming growth factor beta activator LRRC33 (NRROS), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 73.5kDa. Extracellular Domain: 19-650aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex. May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Leucine-rich repeat-containing protein 33; LRRC33 |
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| Gene, Accession, CAS # | NRROS, UniProt: Q86YC3 |
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| Catalog # | RPC20693 |
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| Order / More Info | Recombinant Human Transforming growth factor beta activator LRRC33 (NRROS), partial from BIOMATIK |
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| Product Specific References | n/a |
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