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| Product Name | Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 627-837) protein (His tag) |
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| Description | Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. STAT6 has been shown to interact with EP300, CREB-binding protein, NFKB1, Nuclear receptor coactivator 1, IRF4 and SND1.Alternative Names: Signal Transducer and Activator of Transcription 6, IL-4 Stat, STAT6 |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | D12S1644|IL-4-STAT|STAT6B|STAT6C |
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| Gene, Accession, CAS # | Gene ID: 6778 |
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| Catalog # | ABIN1692357 |
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| Order / More Info | Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 627-837) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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