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| Product Name | Recombinant Rat COMM domain-containing protein 5 (Commd5) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 31.8kDa. Full Length of Mature Protein: 2-224aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Rattus norvegicus (Rat). May modulate activity of cullin-RING E3 ubiquitin ligase complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Hypertension-related calcium-regulated gene protein (HCaRG) |
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| Gene, Accession, CAS # | Commd5, UniProt: Q9ERR2 |
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| Catalog # | RPC26219 |
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| Order / More Info | Recombinant Rat COMM domain-containing protein 5 (Commd5) from BIOMATIK |
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| Product Specific References | n/a |
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