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| Product Name | NSC-663284 |
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| Description | NSC-663284 is a potent, selective and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for Cdc25A, Cdc25B2, and Cdc25C, respectively). Displays > 20- and > 450-fold selectivity over VHR and PTP1B phosphatases respectively. Arrests cells at both G1 and G2/M phase and blocks cdk2 and cdk1 activation. Blocks proliferation of a range of human tumor cell lines (IC50 = 0.2 - 35 µM). MW: 321.76. Purity ≥98% |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
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| Gene, Accession, CAS # | CAS: 383907-43-5 |
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| Catalog # | B1809-1 |
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| Order / More Info | NSC-663284 from BIOVISION, INC. |
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| Product Specific References | n/a |
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