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| Product Name | NSC 23766 |
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| Description | Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotypes in prostate cancer cells. Purity 99%. MW (observed): 530.97 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride |
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| Gene, Accession, CAS # | CAS: 1177865-17-6 |
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| Catalog # | 2161/10 |
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| Price | |
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| Order / More Info | NSC 23766 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 17157450, 19596849, 19632255, 20336666, 20860838, 21134286, 21156169, 21430067, 21876037, 22278715, 22415826, 22430126, 22505612, 23064517, 23505566, 23524265, 23665174, 24091327, 24096906, 24116978, 24160245, 24167244, 24173803, 24257023, 24574401, 24675552, 24790223, 24962779, 25202979, 25278023, 25319697, 25631101, 25922533, 25991673, 26134656, 26207907, 26238253, 26333167, 26412398, 26414403, 26456232, 26535079, 26582975, 26667040, 26674641, 27221788, 27525568, 28524846, 29271742 |
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