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Product Name | HLA-DRB1, Recombinant, Human, aa30-227, His-Tag |
Description | Purity ~85% (SDS-PAGE). HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is ~26-28kD. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Source: Recombinant corresponding to aa30-227 from human HLA-DRB1 protein, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~25.2kD (219aa) Applications: Suitable for use in SDS-PAGE. |
Size | 100ug, 500ug |
Concentration | n/a |
Applications | n/a |
Other Names | HLA-DRB1, Recombinant, Human, aa30-227, His-Tag (Major Histocompatibility Complex, Class II, DR beta 1, DRB1, HLA DRB1, HLA-DR1B) |
Gene, Accession, CAS # | Accession: NP_002115 |
Catalog # | 218226 |
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Order / More Info | HLA-DRB1, Recombinant, Human, aa30-227, His-Tag from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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