| 产品详情 |
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| Antigenic Specificity | DLL3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 3-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DLL3 Polyclonal Antibody. Delta-like protein 3 is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway. |
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| Immunogen | n/a |
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| Other Names | SCDO1, delta-like protein 3, delta3, drosophila Delta homolog 3 |
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| Gene, Accession # | Entrez: 10683, 13389; Uniprot: O88516, Q9NYJ7 |
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| Catalog # | PA5-23448 |
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| Price | |
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| Order / More Info | DLL3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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