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Product Name | MGMT, Recombinant, Human, aa1-207, His-Tag (Methylated-DNA--Protein-cysteine Methyltransferase) |
Description | Purity ~90% (SDS-PAGE). Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Source: Recombinant protein corresponding to aa1-207 from human MGMT, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~25.6kD AA |
Size | 10ug, 50ug, 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | 6-O-methylguanine-DNA methyltransferase, MGMTO-6-methylguanine-DNA-alkyltransferase |
Gene, Accession, CAS # | SwissProt: P16455 |
Catalog # | 374204 |
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Order / More Info | MGMT, Recombinant, Human, aa1-207, His-Tag (Methylated-DNA--Protein-cysteine Methyltransferase) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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