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| Product Name | HAA,O, 1-286aa, Human, His tag, E Coli |
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| Description | MW: 35kDa (310aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. HAAO is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. This protein catalyzes the synthesis of quinolinic acid (QuIN) from 3-hydroxyanthranilic acid. QuIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QuIN may participate in the pathogenesis of neurologic and infl |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by BCA assay) |
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| Applications | SDS-PAGE |
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| Other Names | [3-hydroxyanthranilate 34-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-HAO; HAO] |
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| Gene, Accession, CAS # | HAAO, Gene ID: 23498, Accession: NP_036337 |
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| Catalog # | MBS204540 |
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| Order / More Info | HAA,O, 1-286aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Malherbe P., et al. (1994) J Biol Chem. 13;269 (19):13792-7. |
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