| 产品详情 |
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| Antigenic Specificity | SEC14L1 |
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| Clone | OTI3A6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SEC14L1 Monoclonal Antibody (OTI3A6). May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608). |
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| Immunogen | n/a |
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| Other Names | PRELID4A, SEC14L, SEC14-like protein 1 |
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| Gene, Accession # | Entrez: 6397; Uniprot: Q92503 |
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| Catalog # | MA5-27082 |
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| Price | |
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| Order / More Info | SEC14L1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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