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| Product Name | Recombinant Mouse ACTRIIB / ACVR2B Protein (His tag) |
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| Description | MW: 56,853 Da. Purity >94 % as determined by SDS-PAGE. Background: ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of skeletal muscle growth, is regarded as a potential therapeutic target and binds to ACVR2B effectively, and to a lesser extent, to ACVR2A. The structure of human ACVR2B kinase domain in complex with adenine establi |
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| Size | 0.05 mg, 0.1 mg |
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| Concentration | n/a |
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| Applications | The recombinant mouse ACTRIIB/ACVR2B comprises 127 amino acids and has a predicted molecular mass of 14.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmACVR2B is approximately 33-37 kDa due to glycosylation. |
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| Other Names | [ActRIIB, ACVR2B, MGC118477] |
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| Gene, Accession, CAS # | ACTRIIB / ACVR2B, Gene ID: 11481, Accession: NP_031423.1 |
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| Catalog # | MBS2547123 |
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| Price | |
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| Order / More Info | Recombinant Mouse ACTRIIB / ACVR2B Protein (His tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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