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| Product Name | EYA2, 244-514aa, Human, His tag, E Coli |
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| Description | MW: 33.2 kDa (295aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. EYA2, also known as eyes absent homolog 2, is a member of tyrosine phosphatase family that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). This protein promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Recombinant human |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Eyes absent homolog 2; EAB1; MGC10614] |
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| Gene, Accession, CAS # | EYA2, Gene ID: 2139, Accession: AAH08803 |
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| Catalog # | MBS204489 |
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| Order / More Info | EYA2, 244-514aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Krishnan N., et al. (2009) J. Biol. Chem. 284:16066-16070; Fan X., et al. (2000) J. Biol. Chem. 275:32129-32134 |
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