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| Product Name | LIGHT, Human Recombinant |
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| Description | LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions. MW: 20.0-22.5 kDa. Purity ≥ 95% |
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| Size | 3 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | TNFSF14, HVEM-L, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, Herpesvirus entry mediator ligand, CD258, LIGHT |
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| Gene, Accession, CAS # | Accession: O43557 |
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| Catalog # | P1291-3 |
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| Price | |
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| Order / More Info | LIGHT, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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