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| Product Name | PTEN, 1-403aa, Human, His tag, E.coli |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mM EDTA, 2mM DTT, 100mM NaCl, and 20% glycerol . PTEN, also known as phosphatase and tensin homolog, is a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein acts as both a dual-specificity protein phosphatase and a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate. PTEN negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. Recombinant PTEN protein was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 100ug, 20ug, 4ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Phosphatase and tensin homolog, BZS, MHAM, MMAC1, PTEN1, TEP1, Phosphatase and tensin homolog, PTEN, PTEN1, mutated in multiple advanced cancers 1, |
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| Gene, Accession, CAS # | NP 000305 |
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| Catalog # | ATGP0357 |
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| Order / More Info | PTEN, 1-403aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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