| 产品详情 |
| Edit |   |
|---|
| Product Name | Caspase-3 Proform, mouse recombinant |
|---|
| Description | Caspase-3 (also know as CPP32, Yama and apopain) is a member of the caspase family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. Proteolytic processing of this inactive proenzyme generates the 17 kD and 12 kD subunits which, when assembled as a tetramer (a pair of heterodimers), form the active caspase. Cascades of caspase activation have been shown to be key signal-transducing events in apoptosis. Procaspase-3, like other procaspases with short N-terminal prodomains, is considered to be a downstream or ``effector'' enzyme. Pro-caspase-3 can be cleaved and activated by caspase-8 and -10 which are themselves activated through interaction with death ligand receptor/adapter protein complexes (e.g., Fas/FADD). |
|---|
| Size | 5 µg |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Caspase-3, Short name=CASP-3, Apopain, Cysteine protease CPP32, Short name=CPP-32, FLICE, Protein Yama, SREBP cleavage activity 1, Short name=SCA-1 |
|---|
| Gene, Accession, CAS # | CASP3, Gene ID: 12367, Accession: Q8BNT4 |
|---|
| Catalog # | 1183P-5 |
|---|
| Price | |
|---|
| Order / More Info | Caspase-3 Proform, mouse recombinant from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|