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| Product Name | PYCR1, 1-319aa, Human, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol. PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | Enzyme activity |
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| Other Names | Pyrroline-5-carboxylate reductase 1, ARCL2B, P5C, P5CR, PIG45, PP222, PRO3 |
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| Gene, Accession, CAS # | NP 008838 |
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| Catalog # | ATGP0811 |
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| Order / More Info | PYCR1, 1-319aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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