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| Product Name | CDCA8, 19-280aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 1mM EDTA, 0.2M NaCl. CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein may be required to direct the CPC to centromeric DNA. Deletion of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach. Recombinant human CDCA8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Cell division cycle-associated protein 8, Borealin, Dasra-B, PESCRG3 |
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| Gene, Accession, CAS # | NP 060571 |
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| Catalog # | ATGP1050 |
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| Order / More Info | CDCA8, 19-280aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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