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| Product Name | RPS6KB1, 1-525aa, Human, His-tag, Baculovirus |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 50mM Tris-HCl (pH 7.5) containing 30% glycerol, 0.5M NaCl, 2mM DTT, 0.1mM PMSF. RPS6KB1, also known as ribosomal protein S6 kinase beta-1 isoform a, is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. Phosphorylation of S6 induces protein synthesis at the ribosome. The phosphorylation of p70S6K at threonine 389 has been used as a hallmark of activation by mTOR and correlated with autophagy inhibition in various situations. However, several recent studies suggest that the activity of p70S6K plays a more positive role in the increase of autophagy. Recombinant human RPS6KB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Ribosomal protein S6 kinase beta-1 isoform a, RPS6KB1, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, PS6K, S6K, S6K-beta-1, S6K1, STK14A |
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| Gene, Accession, CAS # | NP 003152 |
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| Catalog # | ATGP3741 |
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| Order / More Info | RPS6KB1, 1-525aa, Human, His-tag, Baculovirus from ATGen |
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| Product Specific References | n/a |
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