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| Product Name | TIFA, 1-184aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT. TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | TRAF-interacting protein with FHA domain-containing protein A, T2BP, T6BP, TIFAA |
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| Gene, Accession, CAS # | NP 443096 |
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| Catalog # | ATGP1414 |
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| Order / More Info | TIFA, 1-184aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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