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| Product Name | TMED10, 32-185aa, Human, His tag, E.coli |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol. . TMED10 is a member of the EMP24/GP25L/p24 family and a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. Recombinant human TMED10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 100ug, 20ug, 4ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Transmembrane emp24 domain-containing protein 10, p23, P24(DELTA), S31I125, S31III125, Tmp-21-I, TMP21 |
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| Gene, Accession, CAS # | NP 006818 |
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| Catalog # | ATGP2253 |
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| Order / More Info | TMED10, 32-185aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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