| 产品详情 |
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| Antigenic Specificity | CD309 |
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| Clone | A16085I |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD309 (VEGFR2). CD309, also known as VEGF-R2, KDR, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, and VEGF-D splice isoforms. Activation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration. |
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| Immunogen | Recombinant Human VEGFR2-Fc Chimera |
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| Other Names | VEGFR2, KDR |
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| Gene, Accession # | Gene ID: 3791 |
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| Catalog # | 374002 |
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| Price | |
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| Order / More Info | CD309 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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