| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | FBXO7 |
|---|
| Clone | W16207A |
|---|
| Host Species | Rat |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a, κ |
|---|
| Format | peroxidase (HRP) conjugate |
|---|
| Size | 25 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | HRP anti-FBXO7. F-box only protein 7 (FBXO7) is involved in the ubiquitination process during protein degradation. FBXO7 is a subunit of the SCF (SKP1/cullin-1/F-box protein) complex. The scaffold proteins cullin-1 and SKP1, the RING subunit Rbx1 together with the substrate-recruiting subunit FBXO7 form a functional E3 ubiquitin ligase. FBXO7 is implicated in Parkinson’s disease. In addition to reduced proteasome activity, loss of FBXO7 in mice leads to Parkinsonism-like phenotype. Human FBXO7 is mainly localized to the nucleus, while the mutation observed in patients with parkinsonian-pyramidal syndrome leads to impaired nuclear localization of this protein. |
|---|
| Immunogen | Human FBXO7 recombinant protein (1-250 a.a.) expressed in E. coli. |
|---|
| Other Names | F-box only protein 7 |
|---|
| Gene, Accession # | Gene ID: 25793 |
|---|
| Catalog # | 853503 |
|---|
| Price | |
|---|
| Order / More Info | FBXO7 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|