| 产品详情 |
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| Product Name | HBX 41108 |
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| Description | An inhibitor of USP7 (IC50 = 424 nM); dose-dependently inhibits USP7-mediated p53 deubiquitination in a cell-free assay (IC50 = ~0.8 µM) and in vitro; selective for USP7 over a panel of proteases including aspartic, serine, and metalloproteases (IC50s = >10 µM), several cysteine proteases (IC50s = >1 and >10 µM), and the deubiquitinating enzymes UCH-L1 (IC50 = >1 µM) and SENP1 (IC50 = >10 µM; increases p53 levels; inhibits proliferation of HCT116 cells (IC50 = ~1 µM); induces apoptosis in HCT116 cells |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HBX41108 41,108 USP-7 HEK-293 metallo metalloproteinase metalloprotease DUB de-ubiquitinating deubiquitinase UCHL1 SENP-1 HTC-116 HBX41108 |
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| Gene, Accession, CAS # | CAS: 924296-39-9 |
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| Catalog # | 23759-10 |
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| Price | |
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| Order / More Info | HBX 41108 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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