| 产品详情 |
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| Product Name | HBX-41108 |
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| Description | HBX-41108 is a potent inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 µM). HBX-41108 treatment stabilizes p53, activates the transcription of a p53 target gene without inducing genotoxic stress, and inhibits cancer cell growth. Also induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. MW: 266.64. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
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| Gene, Accession, CAS # | CAS: 924296-39-9 |
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| Catalog # | 9608-5 |
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| Order / More Info | HBX-41108 from BIOVISION, INC. |
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| Product Specific References | n/a |
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