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| Product Name | HBX 41108 |
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| Description | Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. Purity 98%. MW (observed): 266.64 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
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| Gene, Accession, CAS # | CAS: 924296-39-9 |
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| Catalog # | 4285/10 |
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| Price | |
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| Order / More Info | HBX 41108 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19671755 |
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| 产品资料 |
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