| 产品详情 |
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| Product Name | GSK2292767 |
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| Description | A potent and selective inhibitor of PI3Kδ (Ki = 79 pM); has >1,000-fold selectivity for PI3Kδ over isoforms PI3Kα, PI3Kβ, and PI3Kγ (Kis = 501, 630, and 501 nM, respectively); >100-fold selective for PI3Kδ over a panel of 250 kinases; inhibits IFNγ and IL-2 production (IC50s = 1.9 and 3.16 nM, respectively) in a human lung parenchyma assay; protects against eosinophil recruitment (ED50 = 35 µg/kg) in the brown Norway rat acute ovalbumin model of Th2-driven lung inflammation, |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1364798-56-0 1703742-07-7 GSK-2292767 COPD anti-inflammatory infective autoimmune auto-immune IL2 IFNγ α β γ |
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| Gene, Accession, CAS # | CAS: 1254036-66-2 |
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| Catalog # | 21757-25 |
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| Order / More Info | GSK2292767 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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