| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | FcRL4 |
|---|
| Clone | 413D12 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2b, κ |
|---|
| Format | TotalSeq™-A oligomer conjugate |
|---|
| Size | 10 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | TotalSeq™-A0828 anti-human CD307d (FcRL4). FcRL4 (Fc receptor-like 4) is a 57 kD single pass type I transmembrane protein that exhibits 4 Ig like C2 domains. Also known as ITRA1, IGFP2, and FcRH4, FcRL4 is predominately found on a subset of memory B cells. Activation of FcRL4 contributes to B cell receptor inhibition through activation of the tyrosine kinases SHP-1 and 2. FcRL4's nascent loci is 1q23.1; however, breakpoint mutations are associated with multiple myeloma and non-Hodgkins lymphoma. Increased FcRL4 expression on memory B cells has also been observed in HIV viremic patients. FcRL4 predominately binds aggregated IgA, binds weakly with IgG3 and IgG4, and does not bind IgG1 and IgG2. |
|---|
| Immunogen | P815 cells transfected with FcRL4 |
|---|
| Other Names | FcRL4 (Fc receptor-like 4), IRTA1, IGFP2 |
|---|
| Gene, Accession # | Gene ID: 83417 |
|---|
| Catalog # | 340209 |
|---|
| Price | |
|---|
| Order / More Info | FcRL4 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|