| 产品详情 |
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| Product Name | A2m, Recombinant, Rat, aa620-750, His-Tag (Alpha-2-Macroglobulin) |
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| Description | Purity ~90% (SDS-PAGE). Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme rains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. Source: Recombinant protein corresponding to aa620-750 from rat A2m, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~16.9kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P06238 |
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| Catalog # | 372096 |
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| Order / More Info | A2m, Recombinant, Rat, aa620-750, His-Tag (Alpha-2-Macroglobulin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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