| 产品详情 |
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| Antigenic Specificity | CD94 |
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| Clone | 18d3 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | PE-Cy7 conjugate |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Cy7 anti-mouse CD94. CD94 is a 43/39 kD C-type lectin, also known as Kp43. It is present on all NK cells, NKT cells, and a subset of CD8-positive T lymphocytes in most mouse strains. CD94 is a type-II transmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail. CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediate signal transduction. When associated with NKG2A, the complex triggers inhibition; when associated with NKG2C, the complex triggers stimulation. The receptor complex of CD94 and NKG2 receptors bind to the ligand, Qa-1, and are thought to play a role in maintaining self-tolerance in developing NK cells. |
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| Immunogen | CHO cells expressing the C57BL/6 alleles of CD94 and NKG2A |
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| Other Names | Kp43 |
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| Gene, Accession # | Gene ID: 16643 |
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| Catalog # | 105510 |
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| Price | |
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| Order / More Info | CD94 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17114434 |
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