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| Product Name | CLP 257 |
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| Description | Selective KCC2 K+-Cl- cotransporter activator (EC50 = 616 nM). Exhibits selectivity for KCC2 over other KCC family members, NKCC1 and GABAA receptors, as well as 55 other receptors. Enhances Cl- transport and increases KCC2 plasma membrane expression in spinal slices with reduced KCC2 function. Alleviates hypersensitivity in rats with peripheral nerve injury. Purity 98%. MW (observed): 307.34 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone |
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| Gene, Accession, CAS # | CAS: 1181081-71-9 |
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| Catalog # | 5242/50 |
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| Price | |
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| Order / More Info | CLP 257 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 27500406 |
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| 产品资料 |
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