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Product Name | Neuromedin U-8 (porcine) |
Description | Purity ~95%. Purified by HPLC. Neuromedin U (or NmU) is a neuropeptide found in the brain of humans and other mammals, which has a number of diverse functions including contraction of smooth muscle, regulation of blood pressure, pain perception, appetite, bone growth, and hormone release. It was first isolated from the spinal cord in 1985, and named after its ability to cause smooth muscle contraction in the uterus. Neuromedin U is a highly conserved neuropetide present in many species, existing as multiple isoforms. For example, in humans it is a 25 amino acid peptide (U-25) in rats it is 23-aas long (U-23) and it has been found to be as low as 8-aas long in some mammals. NMU-8 is identical to the C terminus of NMU-25, thus is the most highly conserved region of the entire peptide. The relative contribution of the different isoforms to the biological function of neuromedin U is generally not well understood. Neuromedin U, like many neuroactive peptides, is amidated at the C-terminus, |
Size | 5mg |
Concentration | n/a |
Applications | n/a |
Other Names | Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 |
Gene, Accession, CAS # | n/a |
Catalog # | N2171-80S |
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Order / More Info | Neuromedin U-8 (porcine) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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