| 产品详情 |
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| Antigenic Specificity | EFCAB4A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EFCAB4A Polyclonal Antibody. EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. |
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| Immunogen | n/a |
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| Other Names | CRACR2B; CRAC channel regulator 2B; EF-hand calcium-binding domain-containing protein 4A; calcium release-activated calcium channel regulator 2B |
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| Gene, Accession # | Entrez: 213573, 283229, 309112; Uniprot: B0BNK9, Q80ZJ8, Q8N4Y2 |
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| Catalog # | PA5-21059 |
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| Price | |
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| Order / More Info | EFCAB4A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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