| 产品详情 |
| Edit |   |
|---|
| Product Name | Interleukin 6 Receptor, Recombinant, Human (IL-6R) |
|---|
| Description | Purity ≥98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug (1EU/ug). The IL-6 receptor system consists of two chains, IL-6R alpha and gp130. The IL-6R alpha is the binding component speci?c to the IL-6, but does not transduce a signal alone. On the contrary, gp130 transmits signals not only of IL-6, but also IL-6 related cytokines, i.e. LIF, OSM, CNTF, IL-11 and CT-1. The low af?nity binding sites for IL-6, is composed of IL-6R alpha alone. At low concentrations, soluble IL-6R alpha acts as an agonist of IL-6 activity. Recombinant human sIL-6R alpha is a 37.6kD protein, consisting of the extra cellular domain of the sIL-6R alpha chain (338 amino acids). Biological Activity: The ED50 as determined by its' ability to intensify the IL-6 induced growth inhibition of murine M1 cells is ≤5.0ng/ml, in the presence of 20ng/ml of rhIL -6. Amino Acid Sequence: LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH WVLRKPAAGS HPSRWAGMGR RLLLRSVQLH ASGNYSCYRA GRPAGTVHLL VDVPPEEPQL SCFRKSPLSN VCEWGPRSTP SLTTKAVLLV |
|---|
| Size | 5ug, 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | I8428-39J |
|---|
| Price | |
|---|
| Order / More Info | Interleukin 6 Receptor, Recombinant, Human (IL-6R) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|