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| Product Name | Recombinant Rat NADPH oxidase 4 |
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| Description | 210-424aa; Extracellular Domain. MW: 40.6kD. Purity >90% as determined by SDS-PAGE. Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli), 0.2 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Kidney oxidase-1; KOX-1; Kidney superoxide-producing NADPH oxidase] |
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| Gene, Accession, CAS # | Nox4, Gene ID: 85431, Accession: NP_445976.1 |
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| Catalog # | MBS969581 |
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| Order / More Info | Recombinant Rat NADPH oxidase 4 from MYBIOSOURCE INC. |
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| Product Specific References | Novel gp91(phox) homologues in vascular smooth muscle cellsnox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways.Lassegue B., Sorescu D., Szoecs K., Yin Q., Akers M., Zhang Y., Grant S.L., Lambeth J.D., Griendling K.K.Circ. Res. 88:888-894(2001) A novel superoxide-producing NAD(P)H oxidase in kidney.Shiose A., Kuroda J., Tsuruya K., Hirai M., Hirakata H., Naito S., Hattori M., Sakaki Y., Sumimoto H.J. Biol. Chem. 276:1417-1423(2001) Distinct subcellular |
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