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Product Name | RO-3306 ((5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one) |
Description | Purity ≥95% (NMR). Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M. Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards. Synonyms: (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one |
Size | 1mg, 5mg |
Concentration | n/a |
Applications | n/a |
Other Names | (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one |
Gene, Accession, CAS # | CAS: 872573-93-8 |
Catalog # | 45258 |
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Order / More Info | RO-3306 ((5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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