| 产品详情 |
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| Antigenic Specificity | SERPINB3 |
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| Clone | OTI1A12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:4000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SERPINB3 Monoclonal Antibody (OTI1A12). Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase. In 1985, Dr. Jim Travis and Dr. R.W. Carrell designated an emerging family of serine protease inhibitors as the serpin fam-ily, which share homology in both primary amino acid sequence and tertiary structure. Serpins contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive. Aberrant ex-pression of |
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| Immunogen | n/a |
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| Other Names | HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A, protein T4-A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3, serpin B3, squamous cell carcinoma antigen 1 |
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| Gene, Accession # | Entrez: 6317; Uniprot: P29508 |
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| Catalog # | MA5-26288 |
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| Price | |
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| Order / More Info | SERPINB3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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