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Product Name | Olfactomedin-2, Recombinant, Human |
Description | Purity ≥90% (SDS-PAGE). Olfactomedin-2 (OLFM2, OM2), also called OlfC or neuronal olfactomedin-related endoplasmic reticulum- localized-2 (Noelin-2) i s a 50kD (predicted), secreted member of the olfactomedin/noelin family of proteins. Since Noelin-2 has also been used to designate an alternately spliced form of Noelin-1, Olfactomedin-2 is the less ambiguous name. Olfactomedin domain-containing proteins are of ten found in neural tissues. Human Olfactomedin-2 expressed sequence tags have mainly been found in the brain and eye, and RNA in the cerebellum. In zebrafish, Olfactomedin-2 expression is developmentally regulated and, like Noelin-1, may play a role in neural crest cell differentiation. The human Olfactomedin-2 cDNA encodes a 20aa signal sequence and a 454 mature protein that contains two coiled-coil regions (aa58-85 and 136-193) and an Olfactomedin domain (aa194-446). Mature human Olfactomedin-2 shares 98% aa identity with rat, bovine and equine, 97% with mouse and canine, 81% |
Size | 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | Olfactomedin-2, Recombinant, Human (OLFM2, OM2, neuronal olfactomedin-related endoplasmic reticulum- localized-2, Noelin-2) |
Gene, Accession, CAS # | Accession: NP_477512 |
Catalog # | O6170-02 |
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Order / More Info | Olfactomedin-2, Recombinant, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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