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| Product Name | GMPS, 1-693aa, Human, His tag, E Coli |
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| Description | MW: 79.2 kDa (717aa). Purity >90% by SDS-PAGE. GMP synthase, also known as GMPS, is involved in purine biosynthesis. Existing as a homodimer, GMPS catalyzes the last step in the GMP synthesis pathway, namely the ATP-dependent amination of XMP to GMP. GMPS contains one GMP-binding domain and one glutamine amidotransferase type-1 domain through which it conveys its catalytic activity. Chromosomal translocations involving the gene encoding GMPS are associated with acute myeloid leukemias, suggestin |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [GMP synthase [glutamine-hydrolyzing]; Glutamine amidotransferase; guanine monophosphate synthetase] |
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| Gene, Accession, CAS # | GMPS, Gene ID: 8833, Accession: NP_003866 |
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| Catalog # | MBS204738 |
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| Order / More Info | GMPS, 1-693aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hirst M., et al. (1994) J Biol Chem. 269:23830-23837.; Nakamura J., et al. (1995) J Biol Chem. 270:23450-23455. |
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