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| Product Name | KIR2DS4, Recombinant, Human, aa1-202 |
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| Description | Purity ~95% (RP-HPLC, SDS-PAGE). Killer-cell immunoglobulin-like receptors (KIRs), are a family of cell surface glycoproteins found on Natural Killer (NK) Cells, which are important cells of the immune system. They control the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This interaction allows them to identify virally infected cells or tumor cells that have a distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, which means that their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. The KIR genes are found in a cluster on chromosome 19q13.4 within the 1Mb leukocyte receptor complex (LRC). KIR molecules are extremely polymorphic, meaning their gene sequences differ significantly between individuals, so that different individuals have different arrays/repertoires of KIR genes. Source: Recombina |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | KIR2DS4, Recombinant, Human, aa1-202 (P58 KIR, CD158, CL-17, Natural Killer-Associated Transcript 8, NKAT-8, Killer Cell Immunoglobulin (Ig)-like Receptor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209052 |
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| Order / More Info | KIR2DS4, Recombinant, Human, aa1-202 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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