| 产品详情 |
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| Product Name | Kir1.1 Inhibitor, VU591 (Inward Rectifier Potassium Channel Kir1.1 Blocker, VU591) |
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| Description | Purity ~98% (HPLC). A cell-permeable, benzoimidazole, renal outer medullary potassium channel (ROMK) blocker that selectively inhibits inward rectifier potassium channel, Kir1K.1 (IC50=240nM), in HEK-293 cells. At 10uM, it displays no effect on Kir2.1, Kir2.3, Kir4.1, and Kir7.1, with 150-fold selectivity over Kir6.2. In addition, it exhibits a modest off-target effect on the GABAA receptor (IC50=6.2uM) among a panel of cardiac and central nervous system ion channels and receptors. Formula: C16H12N6O5 Molecular Weight: 368.3 Solubility: DMSO (100mg/ml, clear, dark brown solution) |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217491 |
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| Order / More Info | Kir1.1 Inhibitor, VU591 (Inward Rectifier Potassium Channel Kir1.1 Blocker, VU591) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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